Spironolactone Tablets 25 mg

Description

Spironolactone tablets at 25 mg per film-coated tablet, bottles of 100, 2,500 mg in total. Spironolactone is a steroidal antimineralocorticoid with antiandrogenic activity at the receptor, approved and widely marketed as a generic in the United States, and it is not a controlled substance. Research use only, not for human consumption, adults 21 and over, with purchase restrictions by state.

Specification

Three strengths are registered for this compound and 25 mg is the one listed here. The count and the content per unit are both on the label, which is what makes the total for spironolactone tablets checkable.

Catalogued in the ancillary compounds, alongside the rest of the anabolics reference stock.

United States regulatory status

Spironolactone is an approved, extensively marketed generic medicine in the United States and is not listed on any federal controlled substance schedule. It sits on the ancillary shelf for chemical reasons, and its regulatory position has nothing in common with the Schedule III compounds elsewhere in this catalogue. Records are at the FDA’s drug approvals and databases and DailyMed.

What spironolactone tablets contain

Spironolactone is a steroid carrying a gamma-lactone ring fused at carbon 17 and a thioacetate group at carbon 7 alpha, molecular mass about 416.6. The sulphur is unusual on a steroid nucleus and it gives the molecule a distinctive mass spectrum, which makes identity confirmation clean.

The published literature classifies it as a competitive antagonist at the mineralocorticoid receptor with activity at the androgen receptor as well. That is receptor pharmacology from in-vitro work, and it is not a statement about spironolactone tablets or about anything it would do in a living organism.

Two thousand five hundred milligrams

25 mg times 100 tablets is 2,500 mg. At $22 that is about $0.009 per milligram, the lowest per-milligram figure in this catalogue. High unit content, high count and a long-established generic supply chain all push in the same direction.

Why price per milligram beats the price on the bottle explains why that number belongs under the price rather than in a footnote.

Reading the lot certificate

Start at the header, not the numbers. The laboratory name, the method reference, the date the sample was received and the lot it came from are what make the rest of the page mean anything. Then the HPLC purity figure for spironolactone tablets, as a percentage of total peak area. Then the mass spectrometry identity confirmation, which is the measured mass set against the expected molecular mass. Then residual solvents in parts per million. The laboratory issuing it has no ownership connection to this company, which is the part that cannot be reconstructed from the figures themselves.

Check the lab before you check the numbers explains why we put the header first, and how to read a certificate of analysis covers the fields in order.

Specifications only

Everything above is a property of spironolactone tablets or of its paperwork. There is no section on use, because there is no version of a use section for this family that we are willing to write, and requests for one are declined rather than quietly ignored.

What we will answer about spironolactone tablets: what the assay returned, what the lot number refers to, what the carrier and preservative are, whether we can ship to a given state. Why research use only is not a legal strategy covers the regulatory background, and the FDA’s drug information pages carry the agency’s own statements.

Packaging notes

We ship spironolactone tablets in the original sealed container with the lot number legible. We do not decant, relabel or combine lots, because a reference material whose lot cannot be named is no longer a reference material. The listing for this item states the storage conditions and the stability window we are willing to stand behind. Nothing is supplied in unmarked packaging, and we will not omit the compound name from a label or a customs declaration.

Research use only, not for human consumption, adults 21 and over, with purchase restrictions by state. Where a state excludes this compound the listing says so before checkout rather than after it. Nothing on this page is offered as a drug, a supplement or a food. The certificate for the lot you receive, and the certificates for the lots we withdrew, are on the lab results page.