Description
The Melanotan I 10mg vial is supplied as a reagent: afamelanotide, a thirteen residue analog of alpha-MSH, lyophilized, sealed and assayed by lot. The fill weight is 10 mg of net peptide content. The powder is white to off-white. Nothing here is addressed to a person, because the material is not for human or veterinary consumption.
The same material is catalogued elsewhere as afamelanotide. The label on the Melanotan I 10mg vial carries the compound, the fill weight and the lot number, and that is the extent of it.
Contents of the Melanotan I 10mg vial
What follows is the specification for the Melanotan I 10mg vial, with the measured figures on the lot certificate.
| Compound. | Melanotan I |
|---|---|
| Vial content. | 10 mg net peptide content |
| Form. | Lyophilized, white to off-white, sealed under vacuum |
| Sequence length. | Thirteen residues |
| Purity. | HPLC, percent of total peak area |
| Identity. | Mass spectrometry against expected mass |
| Water. | Karl Fischer titration, percent by weight |
| Documentation. | Independent certificate of analysis, tied to the lot number |
| Price basis. | About $7.90 per milligram as priced |
| Supplied for. | Laboratory research use only, not for human or veterinary consumption |
The format, the fill weight and the milligram arithmetic
Lyophilization takes the water out without ever letting it be liquid. Freeze, pull a vacuum, and the ice leaves as vapour. Material is supplied in that state because water is the main thing that degrades a peptide, and because a dry solid survives a courier network that a solution would not. The cake takes up much more room than the peptide itself, which is why a small fill can look surprisingly bulky in the vial. Nothing about the Melanotan I 10mg vial is sold by volume.
Doing the division
Milligram content is the unit the Melanotan I 10mg vial is sold in, because it is the only figure that makes two listings comparable. Dividing the listed price by the fill weight gives about $7.90 per milligram. That figure is printed under the price for a reason: a bigger vial almost always looks more expensive and is almost always cheaper per milligram, and the headline price hides that completely. Compare the Melanotan I 10mg vial on that basis rather than on the price of the glass. The case is made at greater length in why price per milligram beats the price on the bottle.
Reading the certificate for this lot
What a certificate of analysis should contain is not mysterious. The compound as named. The lot. When it was tested. The purity figure and the chromatogram it came from. The observed mass against the calculated mass. The water content. Who did the testing. Where any of those are absent, the document is describing less than it appears to describe. The certificate issued with the Melanotan I 10mg vial is specific to the lot and not to the product line.
Testing is contracted out to a laboratory with no ownership tie to the seller. It is a weaker guarantee than people sometimes assume and a stronger one than in house assay, for the plain reason that the people producing the number are not the people selling the vial. Stock is withdrawn from sale where the certificate for the Melanotan I 10mg vial does not support the figures here. See how to read a certificate of analysis and check the lab before you check the numbers.
What the methods actually measure
Residual moisture comes from a Karl Fischer titration, which measures water specifically rather than inferring it from a loss on drying. Two things follow from the number. Water drives hydrolysis, so a drier cake is a more stable cake, and water weighs something, so it occupies part of any gross fill weight. The same methods are run on the Melanotan I 10mg vial as on every other lot on this shelf, and formulae and expected masses for compounds of this class can be checked through PubChem at the NCBI.
Why the name is inconsistent, and how to store the Melanotan I 10mg vial
One compound, several names, is the normal condition here. Internal codes outlive the laboratories that issued them, INCI numbers get reassigned, and nothing in a product title resolves any of it. Some names in this category spell out an intended effect once expanded. Those stay abbreviated, because writing them out would turn a catalogue entry into an assertion about biological activity. The catalogue name carried by the Melanotan I 10mg vial is the one the trade uses, and a trade name is not an identifier.
Handling notes are short. Sealed, dry, cold and dark, at 2 to 8 degrees Celsius for the short term and minus 20 degrees Celsius or below for anything longer. The stability window for the lot is printed on this listing. Keep the certificate with the vial, since the lot number is the only thing joining the two.
Research use only: this vial is a reagent
This is a laboratory reference material. It is not for human or veterinary consumption, it is not a food and it is not a drug. There is no dose on this page, no timing, no route, no site and no reconstitution method, and asking for any of them will not produce them. Bacteriostatic water, diluents and syringes are stocked separately and are not sold as a set with this item. No part of this page describes a use for this material in a person or an animal.
A research use only statement is not a legal strategy and is not treated as one here. Warning letters in this area turned on what the rest of the page said, not on whether a disclaimer was present. See research use only is not a legal strategy, and the FDA warning letter archive.
Withdrawn lots stay published alongside the rest rather than quietly disappearing. The page is a specification, and the specification is all of it. This item sits on the cosmetic peptide shelf, inside the research peptide catalogue, and every certificate we hold is on the lab results page.
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