NAD+ 500mg Vial

Description

The NAD+ 500mg vial is nicotinamide adenine dinucleotide in the oxidized form, a dinucleotide coenzyme rather than a peptide, supplied as lyophilized powder with the purity figure for the lot published beside it. The fill weight is 500 mg of net content. The powder is white to pale yellow and the vial is sealed under vacuum. It is sold as a laboratory reference material and is not for human or veterinary consumption.

The same material is catalogued elsewhere as beta-nicotinamide adenine dinucleotide. It is filed on this shelf by trade convention and not because it belongs to the peptide class, and the chemical name is written out here because it describes a structure rather than an effect. The label on the NAD+ 500mg vial carries the compound, the fill weight and the lot number, and that is the extent of it.

What the NAD+ 500mg vial is

What follows is the specification for the NAD+ 500mg vial, with the measured figures on the lot certificate.

Lyophilized powder, and the price per milligram of the NAD+ 500mg vial

Freeze drying is how a peptide reaches you stable at ambient temperature. The solution is frozen solid, then the ice is pulled off under vacuum instead of being melted, so the water never passes through a liquid phase on the way out. What is left behind is a porous cake. In the vial it may sit as a flat disc, a loose dust, or a thin film part way up the glass. None of those appearances says anything about the contents. Fill weight and the assay figure do. Nothing about the NAD+ 500mg vial is sold by volume.

The arithmetic

Milligram content is the unit the NAD+ 500mg vial is sold in, because it is the only figure that makes two listings comparable. That is around $0.24 per milligram on the price as listed. Milligram content is the unit the whole comparison should run on, and anything else, a per vial price or a per order price, moves with packaging rather than with content. Compare the NAD+ 500mg vial on that basis rather than on the price of the glass. The case is made at greater length in why price per milligram beats the price on the bottle.

The certificate of analysis for the NAD+ 500mg vial

What a certificate of analysis should contain is not mysterious. The compound as named. The lot. When it was tested. The purity figure and the chromatogram it came from. The observed mass against the calculated mass. The water content. Who did the testing. Where any of those are absent, the document is describing less than it appears to describe. The certificate issued with the NAD+ 500mg vial is specific to the lot and not to the product line.

Testing is contracted out to a laboratory with no ownership tie to the seller. It is a weaker guarantee than people sometimes assume and a stronger one than in house assay, for the plain reason that the people producing the number are not the people selling the vial. Stock is withdrawn from sale where the certificate for the NAD+ 500mg vial does not support the figures here. See how to read a certificate of analysis and check the lab before you check the numbers.

What the methods actually measure

Mass spectrometry is the identity check. The instrument measures the mass to charge ratio of the ionised molecule and that measurement is held up against the mass predicted from the sequence. Peptides built by solid phase synthesis can come out one residue short, and a deletion of that kind changes the mass in a way the spectrum will show even where the chromatography looks tidy. The same methods are run on the NAD+ 500mg vial as on every other lot on this shelf, and formulae and expected masses for compounds of this class can be checked through PubMed.

Names, abbreviations and how to keep the NAD+ 500mg vial

Abbreviations here are inherited rather than designed. They come from the groups that first made a compound, from ingredient registers, from development programmes and from vendors, so two listings can look different and be identical. Where an abbreviation expands into a statement about what a compound does, the abbreviation is what appears here, in the title, the web address, the image description and the text alike. The catalogue name carried by this vial is the one the trade uses, and a trade name is not an identifier.

Handling notes are short. Sealed, dry, cold and dark, at 2 to 8 degrees Celsius for the short term and minus 20 degrees Celsius or below for anything longer. The stability window for the lot is printed on this listing. Keep the certificate with the vial, since the lot number is the only thing joining the two.

Research use only, stated plainly

Research use only, not for human or veterinary consumption. That sentence is a description of what is being sold and not a disclaimer appended to something else. There is accordingly no dose, no cycle, no route of administration and no reconstitution guidance anywhere on this page, and the omission is the policy rather than a gap in the copy. No part of this page describes a use for this material in a person or an animal. Bacteriostatic water, sterile diluents and syringes are stocked separately rather than sold as a set with the vial.

The limits of that sentence need stating. A research use only line describes what is sold, it is not a shield, and the enforcement record shows whole product pages being read rather than disclaimers alone. See research use only is not a legal strategy.

Every figure quoted here comes from the document linked above, and older certificates are kept rather than retired. That is the whole of the claim being made. This item sits on the longevity shelf, inside the research peptide catalogue, and every certificate we hold is on the lab results page.